A New Way to Treat Infantile Spasms

Infantile spasms, also known as West Syndrome, are a severe form of childhood epilepsy. Seizures develop during the first year of life and – if seizures cannot be stopped –... Continue Reading

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Improving Symptoms of Depression in Adults with Epilepsy

Depression is a common problem for people living with epilepsy, occurring in up to 50% of adults. In many cases, the depressive symptoms can cause serious problems and affect quality... Continue Reading

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Bridging the Gap Between the Epilepsy Clinic and Community Supports

When first diagnosed, people with epilepsy and their families often have a lot of information to sort through and process, and may not know where to go for support. Ms.... Continue Reading

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Mapping Brain Areas Responsible for Language to Improve Surgery Outcomes

Traditionally, language abilities were thought to only involve two areas of the brain, known as Broca’s and Wernicke’s areas. Based on this understanding, seizure surgery that avoids these areas should... Continue Reading

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Can The Ketogenic Diet Be Safely Started at Home?

The ketogenic diet is typically started in the hospital for safety reasons. This means that the child must wait for a hospital bed to become available, and must spend some... Continue Reading

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Screening for Infantile Spasms

West’s syndrome is a childhood epilepsy syndrome. It leads to drug-resistant seizures known as infantile spasms, abnormal brain activity (referred to as hypsarrhythmia), and in most children, intellectual disability. West’s... Continue Reading

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Do Re-Occurring Seizures Injure the Growing Brain?

After seizure surgery, many children become seizure free. Are these children more likely to have a better quality of life relative to children who still experience repeated seizures? Are there... Continue Reading

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Does Electrical Status Epilepticus in Sleep (ESES) Impair the Growing Brain?

Children with certain rare forms of epilepsy are at risk of having developmental and/or intellectual disabilities. Although the cause of these disabilities is not well understood, they may be linked... Continue Reading

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Creating a Brain Atlas for Image-Guided Seizure Surgery

Seizure surgery is a potential treatment option for people that have focal seizures – seizures that are localized to one area of the brain. One of the goals of seizure... Continue Reading

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Memory and Language Outcomes After Seizure Surgery in Adults with Mesial Temporal Lobe Epilepsy

What are the risks of seizure surgery? What side effects might someone experience after surgery? These frequently asked questions help people with epilepsy determine whether seizure surgery is an appropriate... Continue Reading

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Genetics of Temporal Lobe Epilepsy

Epilepsy is about 7 times more common in people with a genetic syndrome caused by chromosome 22q11.2 microdeletion or 22qCNV. Dr. Danielle Andrade and her team have recently found that... Continue Reading

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Using Brain Patterns to Predict and Stop Seizures

Dr. Jose Luis Perez-Velazquez and his research team at the Hospital for Sick Children have been focused on ways to detect when a seizure will start and then stop it... Continue Reading

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Finding the Seizure Focus in Adults with Temporal Lobe Epilepsy

Temporal lobe epilepsy – where seizures arise from the side of the brain – is one of the most common types of epilepsy. After diagnosis, standard magnetic resonance imaging (MRI;... Continue Reading

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Comparing the Classic Ketogenic Diet to Less Restrictive Diets

In the classic ketogenic diet, fat makes up 90% of the calories. Although proven to be effective for managing seizures, the classic ketogenic diet is strict and can be unpleasant... Continue Reading

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Understanding the Brain Changes that Arise with Cortical Dysplasia

Cortical dysplasia is when brain cells in the cortex (the outer layer of the brain) do not undergo adequate development. People with cortical dysplasia are more likely to develop drug-resistant... Continue Reading

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Epilepsy after Brain Injury

Every year, about half a million people in North America suffer from a severe brain injury (referred to as a traumatic brain injury or TBI). As a result of this... Continue Reading

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Who Will Develop Drug-Resistant Epilepsy?

Anti-seizure medications are the first line of therapy for people with epilepsy. However, about 1 in 3 people with epilepsy have seizures that are not controlled by drugs. When someone... Continue Reading

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