A New Way to Treat Infantile Spasms

Infantile spasms, also known as West Syndrome, are a severe form of childhood epilepsy. Seizures develop during the first year of life and – if seizures cannot be stopped – Continue Reading

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Improving the Transition from Child to Adult Epilepsy Care in Ontario

When children with epilepsy reach a certain age, they must transfer from child (pediatric) to adult hospital care. The transition can be a difficult one, as healthcare providers and support Continue Reading

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What Leads to Sudden Unexpected Death in Epilepsy?

Sudden Unexpected Death in Epilepsy (SUDEP) is defined as the death of an otherwise healthy person with epilepsy that occurs either after a seizure or even when there is no Continue Reading

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Mapping Brain Areas Responsible for Language to Improve Surgery Outcomes

Traditionally, language abilities were thought to only involve two areas of the brain, known as Broca’s and Wernicke’s areas. Based on this understanding, seizure surgery that avoids these areas should Continue Reading

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Screening for Infantile Spasms

West’s syndrome is a childhood epilepsy syndrome. It leads to drug-resistant seizures known as infantile spasms, abnormal brain activity (referred to as hypsarrhythmia), and in most children, intellectual disability. West’s Continue Reading

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The EpLink Genetics Project

Who will develop epilepsy? Who is more likely to develop drug-resistant epilepsy? To address these questions, the EpLink Genetics Project was created to find the genes that may lead to Continue Reading

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Do Re-Occurring Seizures Injure the Growing Brain?

After seizure surgery, many children become seizure free. Are these children more likely to have a better quality of life relative to children who still experience repeated seizures? Are there Continue Reading

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Finding a Cure for Lafora Disease

Lafora disease is a rare type of epilepsy that is likely genetic – caused by either a change in a single gene or a small number of related genes (what Continue Reading

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Epilepsy-Related Deaths in Children

Sudden Unexpected Death in Epilepsy (SUDEP) is defined as the death of an otherwise healthy person with epilepsy that occurs either after a seizure or sometimes when there is no Continue Reading

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Monitoring Brain Waves to Predict Seizures

Researchers are interested in developing computer-based programs that can predict seizures using brain wave patterns and help warn individuals about an upcoming seizure. To create these programs, researchers must first Continue Reading

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Using Brain Patterns to Predict and Stop Seizures

Dr. Jose Luis Perez-Velazquez and his research team at the Hospital for Sick Children have been focused on ways to detect when a seizure will start and then stop it Continue Reading

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Comparing the Classic Ketogenic Diet to Less Restrictive Diets

In the classic ketogenic diet, fat makes up 90% of the calories. Although proven to be effective for managing seizures, the classic ketogenic diet is strict and can be unpleasant Continue Reading

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Using Advanced Brain Imaging to Find Where Seizures Begin

Magnetoencephalography (MEG) is a new technology that can be used to monitor a person’s brain activity. A MEG helmet placed on the head can map out brain activity by identifying Continue Reading

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Improving Working Memory in Children with Epilepsy

Working memory is the ability to briefly hold information in your mind and work with it – such as remembering someone’s phone number while you look for a piece of Continue Reading

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Understanding How Environment and Diet Affect Epilepsy

Infantile spasms are drug-resistant seizures seen in children with West’s Syndrome – a childhood epilepsy syndrome. Infantile spasms begin around the first year of life, typically between the ages of Continue Reading

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Long-term Outcomes of Epilepsy Surgery in Children

After a child with epilepsy has surgery to remove the part of the brain that causes seizures, there is hope that many aspects of that child’s life will improve in Continue Reading

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Mapping Brain Networks in Childhood Epilepsy

To get some of the most accurate brain activity recordings before, during and after a seizure, intracranial electroencephalography (iEEG) is typically used. This technology, where sensors are placed directly onto Continue Reading

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