Diet Therapy

Can The Ketogenic Diet Be Safely Started at Home?

The ketogenic diet is typically started in the hospital for safety reasons. This means that the child must wait for ...
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Healthcare Usage and Impact of the Ketogenic Diet for Children with Epilepsy in Ontario

The ketogenic diet is a well-established and effective treatment for drug-resistant epilepsy. However, the diet is underused because many hospitals ...
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Comparing the Classic Ketogenic Diet to Less Restrictive Diets

In the classic ketogenic diet, fat makes up 90% of the calories. Although proven to be effective for managing seizures, ...
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Does Fish Oil Stop Seizures When Added to a Normal Diet?

Although the classic ketogenic diet – which is high in fats, low in carbohydrates and provides adequate protein – has ...
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Drug Therapy

A New Way to Treat Status Epilepticus at Home

Status epilepticus is a condition in which seizures occur non-stop, one after the other. It is a dangerous condition that ...
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A New Way to Treat Infantile Spasms

Infantile spasms, also known as West Syndrome, are a severe form of childhood epilepsy. Seizures develop during the first year ...
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Testing ‘Medical Marijuana’ in Animals and Humans

Medical marijuana (cannabis) has two major extracts: tetrahydrocannabinol (THC), which makes you feel 'high,' and cannabidiol (CBD), which does not ...
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New Drugs from Rett Syndrome Research

Rett syndrome is a genetic disorder that may result in both intellectual disability and seizures. Using an animal model of ...
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New Drugs Based on the Female Hormone Progesterone

The most common seizures in adults are complex partial seizures, which often start at the sides of the brain - ...
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Owen Barry Pharmaceuticals

In September 2014, Owen Barry Pharmaceuticals (OB Pharma) was launched with funding support from the Ontario Brain Institute, as well ...
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New Drugs Based on the Ketogenic Diet

The ketogenic diet is a high-fat, low-carbohydrate diet that controls drug-resistant seizures. Dr. McIntyre Burnham has found that the ketogenic ...
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Epidemiology and Diagnosis

What Leads to Sudden Unexpected Death in Epilepsy?

Sudden Unexpected Death in Epilepsy (SUDEP) is defined as the death of an otherwise healthy person with epilepsy that occurs ...
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Screening for Infantile Spasms

West’s syndrome is a childhood epilepsy syndrome. It leads to drug-resistant seizures known as infantile spasms, abnormal brain activity (referred ...
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Getting an Accurate Diagnosis After the First Seizure

After a first seizure – or suspected seizure – it is often hard to know if an anti-seizure medication should ...
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Epilepsy-Related Deaths in Children

Sudden Unexpected Death in Epilepsy (SUDEP) is defined as the death of an otherwise healthy person with epilepsy that occurs ...
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Epilepsy after Brain Injury

Every year, about half a million people in North America suffer from a severe brain injury (referred to as a ...
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Who Will Develop Drug-Resistant Epilepsy?

Anti-seizure medications are the first line of therapy for people with epilepsy. However, about 1 in 3 people with epilepsy ...
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Genetics and Epigenetics

The EpLink Genetics Project

Who will develop epilepsy? Who is more likely to develop drug-resistant epilepsy? To address these questions, the EpLink Genetics Project ...
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Finding a Cure for Lafora Disease

Lafora disease is a rare type of epilepsy that is likely genetic – caused by either a change in a ...
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Genetics of Temporal Lobe Epilepsy

Epilepsy is about 7 times more common in people with a genetic syndrome caused by chromosome 22q11.2 microdeletion or 22qCNV ...
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Understanding How Environment and Diet Affect Epilepsy

Infantile spasms are drug-resistant seizures seen in children with West’s Syndrome - a childhood epilepsy syndrome. Infantile spasms begin around ...
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The Epigenetics of Epilepsy

To better understand what may contribute to a diagnosis of epilepsy, we need to understand the epigenetics of epilepsy. Epigenetics ...
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Imaging and Seizure Surgery

Mapping Brain Areas Responsible for Language to Improve Surgery Outcomes

Traditionally, language abilities were thought to only involve two areas of the brain, known as Broca’s and Wernicke’s areas. Based ...
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Referrals for Seizure Surgery

Why don't many people with epilepsy get referred for surgery? Are surgery referrals not being commonly offered at the level ...
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Creating a Brain Atlas for Image-Guided Seizure Surgery

Seizure surgery is a potential treatment option for people that have focal seizures – seizures that are localized to one ...
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Memory and Language Outcomes After Seizure Surgery in Adults with Mesial Temporal Lobe Epilepsy

What are the risks of seizure surgery? What side effects might someone experience after surgery? These frequently asked questions help ...
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Finding the Seizure Focus in Adults with Temporal Lobe Epilepsy

Temporal lobe epilepsy – where seizures arise from the side of the brain – is one of the most common ...
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Using Advanced Brain Imaging to Find Where Seizures Begin

Magnetoencephalography (MEG) is a new technology that can be used to monitor a person’s brain activity. A MEG helmet placed ...
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Understanding the Brain Changes that Arise with Cortical Dysplasia

Cortical dysplasia is when brain cells in the cortex (the outer layer of the brain) do not undergo adequate development ...
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Mapping Brain Networks in Childhood Epilepsy

To get some of the most accurate brain activity recordings before, during and after a seizure, intracranial electroencephalography (iEEG) is ...
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Quality of Life

Can Seizures Cause Depression?

People with epilepsy often have depression, which can be quite severe. Is depression a response to the difficulties of living ...
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Improving Symptoms of Depression in Adults with Epilepsy

Depression is a common problem for people living with epilepsy, occurring in up to 50% of adults. In many cases, ...
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Bridging the Gap Between the Epilepsy Clinic and Community Supports

When first diagnosed, people with epilepsy and their families often have a lot of information to sort through and process, ...
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Improving the Transition from Child to Adult Epilepsy Care in Ontario

When children with epilepsy reach a certain age, they must transfer from child (pediatric) to adult hospital care. The transition ...
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Do Seizures Cause Psychosis?

Depression is not the only mental health issue that is seen in people with temporal lobe epilepsy (epilepsy where seizures ...
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Do Re-Occurring Seizures Injure the Growing Brain?

After seizure surgery, many children become seizure free. Are these children more likely to have a better quality of life ...
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Does Electrical Status Epilepticus in Sleep (ESES) Impair the Growing Brain?

Children with certain rare forms of epilepsy are at risk of having developmental and/or intellectual disabilities. Although the cause of ...
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Impacts of Physical Activity on Health and Quality of Life in Children with Epilepsy

Physical activity can be a useful tool in managing and even preventing many health conditions. Does physical activity have an ...
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Summer Camp Study

Ms. Mary Secco and her team at the Epilepsy Southwestern Ontario have been offering a summer camp program to children ...
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Improving Working Memory in Children with Epilepsy

Working memory is the ability to briefly hold information in your mind and work with it - such as remembering ...
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Long-term Outcomes of Epilepsy Surgery in Children

After a child with epilepsy has surgery to remove the part of the brain that causes seizures, there is hope ...
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Epilepsy and School Readiness in Childhood

Dr. Asuri N. Prasad and his team are studying how well children with epilepsy perform on standardized academic tests when ...
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Seizure Prediction and Brain Stimulation

The Basic Science of Brain Stimulation

Brain stimulation for the treatment of epilepsy is a growing area of research. It has been effective in stopping seizures ...
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Monitoring Brain Waves to Predict Seizures

Researchers are interested in developing computer-based programs that can predict seizures using brain wave patterns and help warn individuals about ...
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Using Brain Patterns to Predict and Stop Seizures

Dr. Jose Luis Perez-Velazquez and his research team at the Hospital for Sick Children have been focused on ways to ...
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A Headset for Detecting Seizures

One of the ways to improve epilepsy care is to develop more advanced technology to detect and monitor seizures. This ...
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