Do Re-Occurring Seizures Injure the Growing Brain?

After seizure surgery, many children become seizure free. Are these children more likely to have a better quality of life relative to children who still experience repeated seizures? Are there differences in their brain structures?

Dr. Elysa Widjaja and her team at the Hospital for Sick Children are working to find out the effects of repeated seizures on children with focal, drug-resistant epilepsy. To do so, they are using advanced brain imaging (3T MRI) and performing neuropsychology tests - including tests that measure intelligence, language, thought processes, memory and physical movements - both before and two years after seizure surgery or standard treatment. The hope is that researchers will gain a better understanding of the need for surgery and its effects on children’s brains, treatment outcomes and quality of life.

By conducting this study, Dr. Widjaja and her team have also found a need to create resource(s) informing parents about what procedures and tests their children will be going through both before and during surgery. Based on this need, they have developed a plain language booklet for parents that will be available online in the upcoming months.

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Status: Recruiting

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