Can Seizures Cause Depression?

People with epilepsy often have depression, which can be quite severe. Is depression a response to the difficulties of living with a chronic disorder, or is it possible that seizures themselves cause depression? An animal study from a group in California has suggested that depression may be caused - or made worse - by repeated seizures that start in the brain regions known as the temporal lobes (located at the sides of the brain). The belief is that the seizures themselves cause depression.

Drs. Brian Scott and Carter Snead tried to replicate this research finding from California. They studied whether repeated seizures that start in the temporal lobe structure, known as the hippocampus, produce “depression-like” behaviours in rats. The data are now complete, and Drs. Scott and Snead found that seizures starting in the temporal lobes do not cause "depression-like" behaviour in rats.

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