A New Way to Treat Infantile Spasms

Image Citation Source by PinkStock Photos, D. Sharon Pruitt used under CC by 2.0
Infantile spasms, also known as West Syndrome, are a severe form of childhood epilepsy. Seizures develop during the first year of life and – if seizures cannot be stopped – they cause significant intellectual disabilities. Currently, infantile spasms are treated with vigabatrin (an anti-seizure medication taken by mouth) or adrenocorticotropin (ACTH, a hormone given by injection), both of which have serious side effects. Dr. Cristina Go and her team believe that prednisolone, a compound that can be given by mouth, may be just as effective in treating infantile spasms and may be much safer. This study will compare prednisolone to vigabatrin. If the data results show that prednisolone is more effective, it may be offered as an alternative to vigabatrin as the "first line" treatment for children with infantile spasms.

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Status: Recruiting

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