Finding the Seizure Focus in Adults with Temporal Lobe Epilepsy

Temporal lobe epilepsy – where seizures arise from the side of the brain – is one of the most common types of epilepsy. After diagnosis, standard magnetic resonance imaging (MRI; typically 1.5 Tesla) is done to look for any injuries or changes in the brain’s structure that may have led to epilepsy.

However, there are a subset of people with temporal lobe epilepsy that appear to have no brain changes when imaged with a standard 1.5 Tesla MRI – so it is unclear exactly where or why seizures begin. Dr. Jorge Burneo and his colleagues in London are trying to determine whether higher resolution (7 Tesla) MRI brain scans can better identify these brain changes. In addition to looking at the brain structure in more detail, they are also looking for changes in brain metabolism (e.g. breakdown of sugars, proteins etc.) with Magnetic Resonance Spectroscopy (MRS) as a way of identifying markers of partial epilepsy and pinpointing where seizures begin.

This study, which is now recruiting participants, is hoping to show that a higher resolution MRI – along with MRS - is needed to accurately identify where seizures start. This information will be essential to finding the brain area that needs to be removed during seizure surgery, ensuring that every surgery is successful.

Researcher(s): , ,
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Status: Recruiting

If you are interested in being a part of this study, please contact us.

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